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Get this from a library cancer causing metals properties and mechanisms of action anna m fan. Epigenetic mechanism of heavy metals homeostasis of metal ions is obtained through complex mechanisms of uptake storage and secretion 4 5however chronic exposure to metals can cause toxic effects and it is a concentration dependent phenomenon 4 5toxic metal ions compete with indispensable ions for biological binding sites altering the function of various molecules and the metal . Did you know heavy metal toxicity can lead to cancer heavy metals are one of the most toxic substances on earth learn what heavy metals are and how they destroy your health discover some methods to remove these toxins from your body and recover from cancer. This comprehensive review highlights the physicochemical properties of cisplatin and related platinum based drugs and discusses its uses either alone or in combination with other drugs for the treatment of various human cancers a special attention is paid to its molecular mechanisms of action and its undesirable side effects. My cancer genome is managed by the vanderbilt ingram cancer center copyright c 2010 2019 my cancer genome vanderbilt ingram cancer center copyright c 2010 2019